Myeloablative conditioning with total body irradiation for AML: Balancing survival and pulmonary toxicity
نویسندگان
چکیده
منابع مشابه
Myeloablative conditioning with total body irradiation for AML: Balancing survival and pulmonary toxicity
PURPOSE The purpose of this study was to compare leukemia-free survival (LFS) and other clinical outcomes in patients with acute myelogenous leukemia who underwent a myeloablative allogeneic stem cell transplant with and without total body irradiation (TBI). METHODS AND MATERIALS Adult patients with acute myelogenous leukemia undergoing myeloablative allogeneic stem cell transplant at Duke Un...
متن کاملFactors associated with pulmonary toxicity after myeloablative conditioning using fractionated total body irradiation
PURPOSE Pulmonary toxicities, including infectious pneumonia (IP) and idiopathic pneumonia syndrome (IPS), are serious side effects of total body irradiation (TBI) used for myeloablative conditioning. This study aimed to evaluate clinical factors associated with IP and IPS following TBI. MATERIALS AND METHODS Fifty-eight patients with hematologic malignancies who underwent TBI before allogene...
متن کاملReduced-toxicity myeloablative conditioning consisting of 8-Gy total body irradiation, cyclophosphamide and fludarabine for pediatric hematological malignancies
Conventional myeloablative conditioning (MAC) regimens often cause severe regimen-related toxicity (RRT). Furthermore, many patients suffer from poor quality of life in accordance with the increase in long-term survivors. We therefore devised a reduced-toxicity myeloablative conditioning (RTMAC) regimen consisting of 8-Gy total body irradiation (TBI), fludarabine (FLU) and cyclophosphamide (CY)...
متن کاملDiode calibration for dose determination in total body irradiation
Background: Total Body Irradiation (TBI) is different from standard radiotherapy in many aspects, so it is not easy to predict the delivered dose to the patient under TBI treatment. Diode dosimetry procedures for surface dose reading can help to define variations of the actually delivered dose from the prescribed one. The aim of this study was to describe the measurements made to calib...
متن کاملFabrication of anthropomorphic phantoms for use in total body photon irradiation and total skin electron irradiation studies
Introduction: Total Skin Electron Therapy (TSET) and Total Body Irradiation (TBI) are kinds of treatment which use electron and photon beams to treat special types of cancers. The aim of these techniques are to deliver uniform dose to the entire skin while minimizing delivered dose to organs at risk. To check the homogeneity of dose delivery in TBI and TSET, using a humanoid ph...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Advances in Radiation Oncology
سال: 2016
ISSN: 2452-1094
DOI: 10.1016/j.adro.2016.07.001